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MEF2A 抗体 (pSer408) (AbBy Fluor® 750)

This anti-MEF2A antibody is a 兔 多克隆 antibody detecting MEF2A in WB, IF (p) 和 IF (cc). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5006682
发货至: 中国

Quick Overview for MEF2A 抗体 (pSer408) (AbBy Fluor® 750) (ABIN5006682)

抗原

See all MEF2A 抗体
MEF2A (Myocyte Enhancer Factor 2A (MEF2A))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This MEF2A antibody is conjugated to AbBy Fluor® 750

应用范围

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Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
  • 抗原表位

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    pSer408

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human MEF2A around the phosphorylation site of Ser408

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    MEF2A (Myocyte Enhancer Factor 2A (MEF2A))

    别名

    MEF2A

    背景

    Synonyms: mef2, ADCAD1, RSRFC4, RSRFC9, Myocyte-specific enhancer factor 2A, Serum response factor-like protein 1, MEF2A

    Background: Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter.

    基因ID

    4205

    UniProt

    Q02078

    途径

    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades
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