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MORG1 抗体 (AA 201-315) (AbBy Fluor® 680)

This anti-MORG1 antibody (ABIN5006522) is a Rabbit Polyclonal antibody detecting MORG1 in WB, IF (cc), IF (p). Suitable for Mouse, Rat.
产品编号 ABIN5006522
发货至: 中国

Quick Overview for MORG1 抗体 (AA 201-315) (AbBy Fluor® 680) (ABIN5006522)

抗原

See all MORG1 (wdr83) 抗体
MORG1 (wdr83) (WD Repeat Domain 83 (wdr83))

适用

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小鼠, 大鼠

宿主

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克隆类型

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  • 2
多克隆

标记

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This MORG1 antibody is conjugated to AbBy Fluor® 680

应用范围

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
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    AA 201-315

    交叉反应

    小鼠, 大鼠

    预测反应

    Human,Dog,Cow,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human MAPK organizer 1

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    MORG1 (wdr83) (WD Repeat Domain 83 (wdr83))

    别名

    MAPK organizer 1

    背景

    Synonyms: MORG1, WD repeat domain-containing protein 83, Mitogen-activated protein kinase organizer 1, MAPK organizer 1, WDR83

    Background: Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. At low concentrations it enhances ERK activation, whereas high concentrations lead to the inhibition of ERK activation. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha via its interaction with EGLN3/PHD3. May promote degradation of HIF1A. May act by recruiting signaling complexes to a specific upstream activator (By similarity). May also be involved in pre-mRNA splicing.

    基因ID

    84292

    UniProt

    Q9BRX9
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