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RUNX1 抗体 (Center)

This anti-RUNX1 antibody is a 兔 多克隆 antibody detecting RUNX1 in WB 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN500646
发货至: 中国

Quick Overview for RUNX1 抗体 (Center) (ABIN500646)

抗原

See all RUNX1 抗体
RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

适用

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人, 小鼠, 大鼠

宿主

  • 144
  • 17
  • 2
  • 1

克隆类型

  • 145
  • 20
多克隆

标记

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This RUNX1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    Center

    特异性

    This antibody detects RUNX1.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Peptide affinity chromatography

    免疫原

    RUNX1 antibody was raised against a 16 amino acid peptide from near the center of human RUNX1.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

    别名

    RUNX1

    背景

    RUNX1 is one of three mammalian RUNX genes that control multiple aspects of embryonic development and are responsible for the pathogenesis of many human diseases. RUNX1 plays major roles in the development of nociceptive sensory neurons in addition to hematopoietic stem cells (HSC) with the exception of the erythroid lineage. During development, Notch signals mediate RUNX1 induction with SCL/GATA/Ets factors, and Wnt signals potentially cooperate with RUNX1 to facilitate adult HSC expansion via cooperative induction of cyclin D, cdk4, and other cell cycle regulators. In turn, RUNX1 regulates cell cycle transitions dependent on functional/physical interactions with other proteins such as HDAC1 and -3, mSin3A, p300, SMAD proteins, and LEF/TCF.Synonyms: 1, AML-1, AML1, AML1-EVI-1, AMLCR1, Acute myeloid leukemia 1 protein, CBF-alpha-2, CBFA2, Core-binding factor subunit alpha-2, EVI-1, PEA2-alpha B, PEBP2-alpha B, PEBP2A2, Polyomavirus enhancer-binding protein 2 alpha B subunit, Runt-related transcription factor, SL3-3 enhancer factor 1 alpha B subunit, SL3/AKV core-binding factor alpha B subunit

    基因ID

    861

    NCBI登录号

    NP_001001890

    UniProt

    Q01196
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