CD180 抗体 (N-Term)
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Quick Overview for CD180 抗体 (N-Term) (ABIN500628)
抗原
See all CD180 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects CD180 / RP105 at N-term.
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交叉反应 (详细)
- Species reactivity (tested):Human
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纯化方法
- Peptide affinity chromatography
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免疫原
- RP105 antibody was raised against a 11 amino acid peptide from near the amino terminus of human RP105.
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亚型
- IgG
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应用备注
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ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- CD180 (CD180 Molecule (CD180))
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别名
- CD180 / RP105
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背景
- Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins. One such protein is RP105, a recently identified homolog to TLR4 that, with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway. It has also been suggested that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes. Despite its predicted molecular weight, RP105 often migrates at 95 - 105 kDa.Synonyms: LY64, Lymphocyte antigen 64, Radioprotective 105 kDa protein
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基因ID
- 4064
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UniProt
- Q99467
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途径
- Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
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