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CD180 抗体 (C-Term)

This anti-CD180 antibody is a 兔 多克隆 antibody detecting CD180 in WB, IHC (p) 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN500626
发货至: 中国

Quick Overview for CD180 抗体 (C-Term) (ABIN500626)

抗原

See all CD180 抗体
CD180 (CD180 Molecule (CD180))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This CD180 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 2
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    C-Term

    特异性

    This antibody detects CD180 / RP105 at C-term).

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse

    纯化方法

    Peptide affinity chromatography

    免疫原

    RP105 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human RP105.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CD180 (CD180 Molecule (CD180))

    别名

    CD180 / RP105

    背景

    Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses.. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins. One such protein is RP105, a recently identified homolog to TLR4 that, with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway. It has also been suggested that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes. Despite its predicted molecular weight, RP105 often migrates at 95 - 105 kDa.Synonyms: LY64, Lymphocyte antigen 64, Radioprotective 105 kDa protein

    基因ID

    4064

    UniProt

    Q99467

    途径

    Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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