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LGMN 抗体 (AA 201-300) (AbBy Fluor® 750)

This anti-LGMN antibody is a 兔 多克隆 antibody detecting LGMN in WB 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5006132
发货至: 中国

Quick Overview for LGMN 抗体 (AA 201-300) (AbBy Fluor® 750) (ABIN5006132)

抗原

See all LGMN 抗体
LGMN (Legumain (LGMN))

适用

  • 56
  • 28
  • 25
  • 3
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  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 51
  • 8

克隆类型

  • 50
  • 9
多克隆

标记

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  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This LGMN antibody is conjugated to AbBy Fluor® 750

应用范围

  • 50
  • 23
  • 13
  • 13
  • 12
  • 7
  • 6
  • 2
  • 1
Western Blotting (WB), Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 9
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-300

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Dog,Cow,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Legumain

    亚型

    IgG
  • 应用备注

    FCM 1:20-100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    LGMN (Legumain (LGMN))

    别名

    Legumain

    背景

    Synonyms: AEP, LGMN1, PRSC1, Legumain, Asparaginyl endopeptidase, Protease, cysteine 1, LGMN

    Background: Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation (By similarity). May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system.

    基因ID

    5641

    UniProt

    Q99538

    途径

    Metabolism of Steroid Hormones and Vitamin D, Activation of Innate immune Response, Toll-Like Receptors Cascades
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