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LCK 抗体 (pTyr505) (AbBy Fluor® 750)

This anti-LCK antibody is a 兔 多克隆 antibody detecting LCK in IF (cc) 和 IF (p). Suitable for 人.
产品编号 ABIN5006103
发货至: 中国

Quick Overview for LCK 抗体 (pTyr505) (AbBy Fluor® 750) (ABIN5006103)

抗原

See all LCK 抗体
LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))

适用

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宿主

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克隆类型

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多克隆

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This LCK antibody is conjugated to AbBy Fluor® 750

应用范围

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Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
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    pTyr505

    预测反应

    Human,Mouse,Rat

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human Lck around the phosphorylation site of Tyr505

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))

    别名

    LCK

    背景

    Synonyms: LCK phospho Y505, LCK phospho Tyr505, p-LCK Tyr505, p56-LCK, Lymphocyte cell-specic protein-tyrosine kinase, LSK, T cell-specic protein-tyrosine kinase, Lck p56, LSK, Lymphocyte Specic Protein Tyrosine Kinase, Membrane associated protein tyrosine kinase, Oncogene lck, P56 LCK, p56LSTRA protein tyrosine kinase, p56lck, pp58 lck, pp58lck, Proto oncogene tyrosine protein kinase LCK, Protooncogene tyrosine protein kinase LCK, T cell specic protein tyrosine kinase, T lymphocyte specic protein tyrosine kinase p56lck, YT 16, YT16, LCK_HUMAN.

    Background: This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq, Jul 2008].

    基因ID

    3932

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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