RIMS2 抗体 (Center)
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北京 101111
Quick Overview for RIMS2 抗体 (Center) (ABIN500608)
抗原
See all RIMS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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特异性
- This antibody detects Rim2. Rim2 is known to exist in multiple isoforms, this antibody should recognize most of them. It is predicted to have no cross-reactivity to other Rim proteins.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Peptide affinity chromatography
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免疫原
- Rim2 antibody was raised against a 17 amino acid peptide near the center of the human Rim2.
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亚型
- IgG
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anti-Regulating Synaptic Membrane Exocytosis 2 (RIMS2) (AA 461-987) antibody
RIMS2 适用: 大鼠, 小鼠, 小鸡, Hamster, 斑马鱼 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Regulating Synaptic Membrane Exocytosis 2 (RIMS2) (C-Term) antibodyRIMS2 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Regulating Synaptic Membrane Exocytosis 2 (RIMS2) (AA 181-260) antibodyRIMS2 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 3C12 unconjugated
anti-Regulating Synaptic Membrane Exocytosis 2 (RIMS2) (AA 909-1076) antibodyRIMS2 适用: 大鼠, 小鼠 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Regulating Synaptic Membrane Exocytosis 2 (RIMS2) (AA 667-943) antibodyRIMS2 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Regulating Synaptic Membrane Exocytosis 2 (RIMS2) (AA 181-260) antibodyRIMS2 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Regulating Synaptic Membrane Exocytosis 2 (RIMS2) (AA 1-1163) antibodyRIMS2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Regulating Synaptic Membrane Exocytosis 2 (RIMS2) (AA 1-1163) antibodyRIMS2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- RIMS2 (Regulating Synaptic Membrane Exocytosis 2 (RIMS2))
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别名
- RIMS2
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背景
- Rab3-interacting molecules (RIMs) are synaptic proteins necessary for neuronal transmission and plasticity. Rim1 and Rim2 proteins are expressed in overlapping but distinct patterns throughout the brain. While the ablation of either gene was not lethal in mice, the deletion of both resulted in postnatal mortality. This lethality is due to a defect in neurotransmitter release, synapses without RIM proteins can still release neurotransmitters but are unable to do so in response to normal Ca2+ triggers. Like Rim1, Rim 2 is thought to be an effector protein for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner.Synonyms: KIAA0751, RAB3IP3, RIM 2, RIM2, Rab-3-interacting molecule 2, Rab-3-interacting protein 3, Regulating synaptic membrane exocytosis protein 2
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基因ID
- 9699
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NCBI登录号
- NP_001093587
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UniProt
- Q9UQ26
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途径
- Hormone Transport, Synaptic Vesicle Exocytosis
抗原
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