KRT17 抗体 (Biotin)
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- 抗原 See all KRT17 抗体
- KRT17 (Keratin 17 (KRT17))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This KRT17 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人
- 纯化方法
- Purified by Protein G.
- 免疫原
- KLH conjugated synthetic peptide derived from human KRT17
- 克隆位点
- 12B1
- 亚型
- IgG
- Top Product
- Discover our top product KRT17 Primary Antibody
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- 应用备注
- WB 1:300-5000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- KRT17 (Keratin 17 (KRT17))
- 别名
- KRT17 (KRT17 产品)
- 别名
- K17 antibody, Krt1-17 antibody, PC antibody, PC2 antibody, PCHC1 antibody, Ka17 antibody, KRT17 antibody, krt16 antibody, si:dkeyp-113d7.7 antibody, KRT14 antibody, keratin 17 antibody, keratin 17 L homeolog antibody, keratin 17, type I antibody, keratin, type I cytoskeletal 17 antibody, Krt17 antibody, KRT17 antibody, krt17 antibody, krt17.L antibody, LOC100737113 antibody, LOC102177275 antibody
- 背景
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Synonyms: Keratin, type I cytoskeletal 17, KRT17, 39.1, Cytokeratin-17, Keratin-17, K17
Background: Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair (By similarity). Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state (By similarity). Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway (By similarity). Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial "stem cells". Acts as a promoter of epithelial proliferation by acting a regulator of immune response in skin: promotes Th1/Th17-dominated immune environment contributing to the development of basaloid skin tumors (By similarity). May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation.
- 基因ID
- 3872
- UniProt
- Q04695
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