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KRT17 抗体 (Biotin)

This anti-KRT17 antibody is a 小鼠 单克隆 antibody detecting KRT17 in WB. Suitable for 人.
产品编号 ABIN5005979
发货至: 中国

Quick Overview for KRT17 抗体 (Biotin) (ABIN5005979)

抗原

See all KRT17 抗体
KRT17 (Keratin 17 (KRT17))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This KRT17 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB)

克隆位点

12B1
  • 交叉反应

    纯化方法

    Purified by Protein G.

    免疫原

    KLH conjugated synthetic peptide derived from human KRT17

    亚型

    IgG
  • 应用备注

    WB 1:300-5000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    KRT17 (Keratin 17 (KRT17))

    别名

    KRT17

    背景

    Synonyms: Keratin, type I cytoskeletal 17, KRT17, 39.1, Cytokeratin-17, Keratin-17, K17

    Background: Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair (By similarity). Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state (By similarity). Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway (By similarity). Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial "stem cells". Acts as a promoter of epithelial proliferation by acting a regulator of immune response in skin: promotes Th1/Th17-dominated immune environment contributing to the development of basaloid skin tumors (By similarity). May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation.

    基因ID

    3872

    UniProt

    Q04695
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