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RGS21 抗体 (Center)

This 兔 多克隆 antibody specifically detects RGS21 in WB, IHC (p) 和 EIA. It exhibits reactivity toward 人.
产品编号 ABIN500587
发货至: 中国
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Quick Overview for RGS21 抗体 (Center) (ABIN500587)

抗原

See all RGS21 抗体
RGS21 (Regulator of G-Protein Signaling 21 (RGS21))

适用

  • 21
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宿主

  • 19
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克隆类型

  • 21
多克隆

标记

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This RGS21 antibody is un-conjugated

应用范围

  • 21
  • 13
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  • 7
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 15
    • 2
    • 2
    • 1
    • 1
    Center

    特异性

    This antibody detects RGS21.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Peptide Affinity Chromatography

    免疫原

    RGS21 antibody was raised against a 16 amino acid peptide near the center of Human RGS21.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 1-2 μg/mL (HepG2 cells as recommended Positive Control). Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    RGS21 (Regulator of G-Protein Signaling 21 (RGS21))

    别名

    RGS21

    背景

    Regulator of G-protein signaling (RGS) proteins contain an 120 amino acid conserved domain, termed the RGS domain, that acts as a GTPase-activating protein that acts to reduce the signal transmitted by the receptor-activated G-alpha subunit. RGS21 is a recently identified member of this family that has been reported to be selectively expressed in subpopulations of taste bud cells and co-expressed with bitter and sweet transduction components such as alpha-gusticin, phospholipase Cbeta2, T1R2/T1R3 sweet taste receptors and T2R bitter taste receptors. Other reports indicate that RGS21 is more widely expressed. Binding assays demonstrate that RGS21 binds alpha-gusticin in a conformation-dependent manner and may do the same with T1R receptors, suggesting that RGS21 may play a role in sweet and bitter taste transduction processes.Synonyms: Regulator of G-protein signaling 21

    基因ID

    431704

    NCBI登录号

    NP_001034241

    UniProt

    Q2M5E4

    途径

    Regulation of G-Protein Coupled Receptor Protein Signaling
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