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KERA 抗体 (AA 201-300) (AbBy Fluor® 680)

This anti-KERA antibody is a 兔 多克隆 antibody detecting KERA in WB, IF (cc) 和 IF (p). Suitable for 人 和 小鼠.
产品编号 ABIN5005845
发货至: 中国

Quick Overview for KERA 抗体 (AA 201-300) (AbBy Fluor® 680) (ABIN5005845)

抗原

See all KERA 抗体
KERA (Keratocan (KERA))

适用

  • 34
  • 20
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 37
  • 2

克隆类型

  • 38
  • 1
多克隆

标记

  • 21
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This KERA antibody is conjugated to AbBy Fluor® 680

应用范围

  • 37
  • 14
  • 12
  • 12
  • 10
  • 8
  • 7
  • 5
  • 3
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 10
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 201-300

    交叉反应

    人, 小鼠

    预测反应

    Rat,Dog,Cow,Sheep,Pig,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Keratocan

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    KERA (Keratocan (KERA))

    别名

    Keratocan

    背景

    Synonyms: CNA2, KERA, KERA_HUMAN, Keratan sulfate proteoglycan keratocan, Keratocan, KTN, SLRR2B.

    Background: Small leucine-rich proteoglycans (SLRPs) such as Decorin, Biglycan, Fibromod-ulin, Keratocan, Lumican and Osteoglycin mediate extracellular matrix organization and are binding partners of TGF Beta. The Decorin core protein binds to growth factors, intercellular matrix molecules such as Fibronectin and Throm-bospondin, and to the Decorin endocytosis receptor. Fibromodulin is a collagen-binding keratan sulphate proteoglycan that influences adhesion processes of connective tissue and plays a role in fibrillogenesis by regulating collagen fibril spacing and thickness. Keratocan (KTN) develops corneal transparency and maintains the stromal matrix structure. Keratocan is a secreted protein in the extracellular matrix that binds to keratan sulfate chains. Keratocan is mainly detected in the cornea, but can also be expressed in trachea, intestine, ovary, lung and skeletal muscle. Defects in the gene encoding for Keratocan can cause cornea plana 2 (CNA2), an autosomal recessive disorder where the forward convex curvature of the cornea is flattened.

    途径

    Glycosaminoglycan Metabolic Process
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