KDM5B 抗体 (AA 65-165) (AbBy Fluor® 680)
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北京 101111
Quick Overview for KDM5B 抗体 (AA 65-165) (AbBy Fluor® 680) (ABIN5005833)
抗原
See all KDM5B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 65-165
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交叉反应
- 人, 大鼠
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预测反应
- Mouse,Dog,Cow,Pig,Horse,Chicken,Guinea Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human KDM5B/Jarid1B
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亚型
- IgG
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anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 231-319) antibody
KDM5B 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1G10 unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 231-319) antibodyKDM5B 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7H3D7 unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 65-165) antibodyKDM5B 适用: 人, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 784-883) antibodyKDM5B 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 231-319) antibodyKDM5B 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) antibodyKDM5B 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 231-319) antibodyKDM5B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4F12 unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (Internal Region) antibodyKDM5B 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))
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别名
- KDM5B
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背景
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Synonyms: CT31, PLU1, PUT1, PLU-1, JARID1B, PPP1R98, RBBP2H1A, Lysine-specific demethylase 5B, Cancer/testis antigen 31, Histone demethylase JARID1B, Jumonji/ARID domain-containing protein 1B, Retinoblastoma-binding protein 2 homolog 1, RBP2-H1, KDM5B, RBBP2H1
Background: Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2 (By similarity).
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基因ID
- 10765
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UniProt
- Q9UGL1
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途径
- Warburg Effect
抗原
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