RCAN2 抗体 (Center)
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北京 101111
Quick Overview for RCAN2 抗体 (Center) (ABIN500577)
抗原
See all RCAN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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特异性
- This antibody detects Calcipressin-2.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Peptide affinity chromatography
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免疫原
- RCAN2 antibody was raised against a 14 amino acid peptide near the center of human RCAN2.
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亚型
- IgG
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anti-Regulator of Calcineurin 2 (RCAN2) (AA 6-37), (N-Term) antibody
RCAN2 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB02309 unconjugated
anti-Regulator of Calcineurin 2 (RCAN2) (AA 88-197) antibodyRCAN2 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Regulator of Calcineurin 2 (RCAN2) (AA 1-225) antibodyRCAN2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Regulator of Calcineurin 2 (RCAN2) (AA 71-120) antibodyRCAN2 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Regulator of Calcineurin 2 (RCAN2) (Middle Region) antibodyRCAN2 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- RCAN2 (Regulator of Calcineurin 2 (RCAN2))
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别名
- Calcipressin-2
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背景
- Regulator of calcineurin 2 (RCAN2), also known as ZAKI4 and DSCR1L1, is expressed as two isoforms differing at their N-terminus. The longer of the two (isoform 1) is expressed exclusively in the brain, while isoform 2 is ubiquitously expressed, with highest expression in brain, heart, and muscle. Both isoforms bind to the catalytic subunit of calcineurin, a Ca++-dependent protein phosphatase involved in several neuronal functions, though their C-terminal region and inhibit calcineurin's activity. Unlike isoform 1 of RCAN2, the expression of the second isoform is not induced by the thyroid hormone T3. RCAN2 is a member of a family of three endogenous calcineurin regulators that are located near the minimal supernumerary fragment of chromosome 21 in individuals with Down syndrome, suggesting that they play a role in this syndrome. Multiple isoforms of RCAN2 are known to exist.Synonyms: DSCR1L1, Down syndrome candidate region 1-like 1, Myocyte-enriched calcineurin-interacting protein 2, RCAN2, Regulator of calcineurin 2, Thyroid hormone-responsive protein ZAKI-4, ZAKI4
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基因ID
- 53901
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UniProt
- Q9JHG2
抗原
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