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RANBP10 抗体 (Center)

This anti-RANBP10 antibody is a 兔 多克隆 antibody detecting RANBP10 in WB, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN500565
发货至: 中国

Quick Overview for RANBP10 抗体 (Center) (ABIN500565)

抗原

See all RANBP10 抗体
RANBP10 (RAN Binding Protein 10 (RANBP10))

适用

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宿主

  • 4

克隆类型

  • 4
多克隆

标记

  • 4
This RANBP10 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 1
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    Center

    交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Peptide affinity chromatography

    免疫原

    RANBP10 antibody was raised against a 15 amino acid peptide near the center of human RANBP10.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    RANBP10 (RAN Binding Protein 10 (RANBP10))

    别名

    RANBP10

    背景

    The RAN binding protein 10 (RANBP10) is a cytoplasmic guanine nucleotide exchange factor that shares high sequence similarity to the MET-interacting protein RANBP9. RANBP10 is expressed in the cytoplasm of mature megakaryocytes (MKs) and platelets where it localizes to polymerized noncentrosomal microtubules. RANBP10 possesses guanine nucleotide exchange factor activity towards RAN, a GTPase involved in nucleocytoplasmic traffic, spindle formation at mitosis, and nuclear envelope assembly during telophase, suggesting that RANBP10 may also be involved in these activities. RANBP10 depletion in vitro caused the disturbance of polymerized filaments in MKs and platelets in RANBP10-null mice exhibited disorders in microtubule filament numbers and localization, indicating that RANBP10 may play a significant role in maintaining microtubule dynamics.Synonyms: KIAA1464, Ran-binding protein 10

    基因ID

    57610

    UniProt

    Q6VN20
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