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- 抗原 See all PRTFDC1 抗体
- PRTFDC1 (phosphoribosyl Transferase Domain Containing 1 (PRTFDC1))
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抗原表位
- Center
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PRTFDC1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects PRTFDC1.
- 交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
- 纯化方法
- Peptide affinity chromatography
- 免疫原
- PRTFDC1 antibody was raised against a 14 amino acid peptide from near the center of human PRTFDC1.
- 亚型
- IgG
- Top Product
- Discover our top product PRTFDC1 Primary Antibody
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anti-phosphoribosyl Transferase Domain Containing 1 (PRTFDC1) (AA 2-225) antibody
PRTFDC1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphoribosyl Transferase Domain Containing 1 (PRTFDC1) (AA 1-225) antibodyPRTFDC1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-phosphoribosyl Transferase Domain Containing 1 (PRTFDC1) (Internal Region) antibodyPRTFDC1 适用: 人, 大鼠, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-phosphoribosyl Transferase Domain Containing 1 (PRTFDC1) (AA 150-199) antibodyPRTFDC1 适用: 人, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-phosphoribosyl Transferase Domain Containing 1 (PRTFDC1) (Internal Region) antibodyPRTFDC1 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-phosphoribosyl Transferase Domain Containing 1 (PRTFDC1) (Middle Region) antibodyPRTFDC1 适用: 人, 大鼠, Pig, 马, 兔, 斑马鱼, 犬 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA. Western blot: 0.5 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- 抗原
- PRTFDC1 (phosphoribosyl Transferase Domain Containing 1 (PRTFDC1))
- 别名
- PRTFDC1 (PRTFDC1 产品)
- 别名
- HHGP antibody, HPRT antibody, hprt1 antibody, hprt1l antibody, zgc:55561 antibody, zgc:86771 antibody, MGC80959 antibody, OTTMUSG00000011667 antibody, Prtfdc1 antibody, phosphoribosyl transferase domain containing 1 antibody, phosphoribosyl transferase domain containing 1 L homeolog antibody, phosphoribosyltransferase domain containing 1 pseudogene antibody, PRTFDC1 antibody, prtfdc1 antibody, Prtfdc1 antibody, prtfdc1.L antibody, Gm13377 antibody
- 背景
- Phosphoribosyl transferase domain containing 1 (PRTFDC1) is highly homologous to the hypoxanthine phosphoribosyltransferase (HPRT1) and may have arisen from a gene duplication event of a common ancestor gene. Recently, it was shown that CpG islands in the PRTFDC1 promoter could be hypermethylated in ovarian cancers and oral squamous-cell carcinomas (OSCC), leading to gene silencing. Restoration of PRTFDC1 expression in OSCC inhibited cell growth in colony-formation assays, while knockdown of PRTFDC1 expression in OSCC that expressed the gene promoted cell growth. These results suggest that PRTFDC1 can act as a tumor-suppressor gene. At least three isoforms of PRTFDC1 are known to exist.Synonyms: HHGP, Phosphoribosyltransferase domain-containing protein 1
- 基因ID
- 56952
- NCBI登录号
- NP_064585
- UniProt
- Q9NRG1
- 途径
- Ribonucleoside Biosynthetic Process
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