PRTFDC1 抗体 (Center)
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Quick Overview for PRTFDC1 抗体 (Center) (ABIN500545)
抗原
See all PRTFDC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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特异性
- This antibody detects PRTFDC1.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Peptide affinity chromatography
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免疫原
- PRTFDC1 antibody was raised against a 14 amino acid peptide from near the center of human PRTFDC1.
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亚型
- IgG
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anti-phosphoribosyl Transferase Domain Containing 1 (PRTFDC1) (AA 2-225) antibody
PRTFDC1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphoribosyl Transferase Domain Containing 1 (PRTFDC1) (Internal Region) antibodyPRTFDC1 适用: 人, 大鼠, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-phosphoribosyl Transferase Domain Containing 1 (PRTFDC1) (AA 1-225) antibodyPRTFDC1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-phosphoribosyl Transferase Domain Containing 1 (PRTFDC1) (AA 150-199) antibodyPRTFDC1 适用: 人, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-phosphoribosyl Transferase Domain Containing 1 (PRTFDC1) (N-Term) antibodyPRTFDC1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-phosphoribosyl Transferase Domain Containing 1 (PRTFDC1) (Middle Region) antibodyPRTFDC1 适用: 人, 大鼠, Pig, 马, 兔, 犬, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 0.5 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- PRTFDC1 (phosphoribosyl Transferase Domain Containing 1 (PRTFDC1))
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别名
- PRTFDC1
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背景
- Phosphoribosyl transferase domain containing 1 (PRTFDC1) is highly homologous to the hypoxanthine phosphoribosyltransferase (HPRT1) and may have arisen from a gene duplication event of a common ancestor gene. Recently, it was shown that CpG islands in the PRTFDC1 promoter could be hypermethylated in ovarian cancers and oral squamous-cell carcinomas (OSCC), leading to gene silencing. Restoration of PRTFDC1 expression in OSCC inhibited cell growth in colony-formation assays, while knockdown of PRTFDC1 expression in OSCC that expressed the gene promoted cell growth. These results suggest that PRTFDC1 can act as a tumor-suppressor gene. At least three isoforms of PRTFDC1 are known to exist.Synonyms: HHGP, Phosphoribosyltransferase domain-containing protein 1
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基因ID
- 56952
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NCBI登录号
- NP_064585
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UniProt
- Q9NRG1
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途径
- Ribonucleoside Biosynthetic Process
抗原
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