TBKBP1 抗体 (C-Term)
Quick Overview for TBKBP1 抗体 (C-Term) (ABIN500543)
抗原
See all TBKBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects Prosapip2.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Peptide affinity chromatography
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免疫原
- Prosapip2 antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human Prosapip2.
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亚型
- IgG
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anti-TBK1 Binding Protein 1 (TBKBP1) (AA 300-350) antibody
TBKBP1 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TBK1 Binding Protein 1 (TBKBP1) (AA 327-427) antibodyTBKBP1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-TBK1 Binding Protein 1 (TBKBP1) (AA 470-497), (C-Term) antibodyTBKBP1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB42418 unconjugated
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应用备注
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ELISA. Western blot. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- TBKBP1 (TBK1 Binding Protein 1 (TBKBP1))
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别名
- TBKBP1
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背景
- Prosapip2 (TBKBP1) is essential for signal transduction during viral infection thus plays a major role in the TNF/NF-kappaB pathway. It is an adaptor protein that constitutively binds TBK1 (TANK-binding kinase) and IKBKE and may play a role in antiviral innate immunity. Prosapip2 is a 615 amino acid adaptor protein belonging to the fibrillar collagen family, consisting of trimers of identical alpha 1 chains which are linked to each other by interchain disulfide bonds. It has a ubiquitous expression with highest levels in ovary, followed by the neuronal system. Prosapip2 binds to TBK1 and helps in the activation of IRF3 which controls the expression of antiviral genes during infection. Recent studies show that Prosapip2 is an interaction partner of ProSAP2/Shank3 and actin, suggesting a role as a linker molecule between postsynaptic density and the cytoskeleton.Synonyms: KIAA0775, ProSAPiP2, Sintbad, TANK-binding kinase 1-binding protein 1, TBK1-binding protein 1
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基因ID
- 9755
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NCBI登录号
- NP_055541
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UniProt
- A7MCY6
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途径
- SARS-CoV-2 Protein Interactome
抗原
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