INPPL1 抗体 (pTyr1135) (AbBy Fluor® 680)
Quick Overview for INPPL1 抗体 (pTyr1135) (AbBy Fluor® 680) (ABIN5005422)
抗原
See all INPPL1 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- pTyr1135
- 
                                            交叉反应
- 人, 小鼠
- 
                                            预测反应
- Dog,Cow,Horse,Rabbit
- 
                                            纯化方法
- Purified by Protein A.
- 
                                            免疫原
- KLH conjugated synthetic phosphopeptide derived from human SHIP2 around the phosphorylation site of Tyr1135
- 
                                            亚型
- IgG
 
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    - 
                                            应用备注
- 
                        IF(IHC-P) 1:50-200
 IF(IHC-F) 1:50-200
 IF(ICC) 1:50-200
- 
                                            限制
- 仅限研究用
 
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- 
    - 
                                            状态
- Liquid
- 
                                            浓度
- 1 μg/μL
- 
                                            缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 
                                            储存液
- ProClin
- 
                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 
                                            储存条件
- -20 °C
- 
                                            储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 
                                            有效期
- 12 months
 
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    - INPPL1 (Inositol Polyphosphate Phosphatase-Like 1 (INPPL1))
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                                            别名
- INPPL1
- 
                                            背景
- 
                        Synonyms: 4, 5-trisphosphate 5-phosphatase 2, 51C protein, EC 3.1.3.n1, inositol polyphosphate phosphatase like 1, Inositol polyphosphate phosphatase like protein 1, Inositol polyphosphate phosphatase-like protein 1, INPPL-1, INPPL1, Phosphatidylinositol 3, Phosphatidylinositol 3,4,5 trisphosphate 5 phosphatase 2, Protein 51C, SH2 domain containing inositol 5' phosphatase 2, SH2 domain-containing inositol 5''-phosphatase 2, SH2 domain-containing inositol phosphatase 2, SHIP-2, SHIP2, SHIP2_HUMAN. Background: The steady state of protein tyrosyl phosphorylation in cells is regulated by the opposing action of tyrosine kinases and protein tyrosine phosphatases (PTPs). Several groups have independently identified a non transmembrane PTP, designated SHPTP1 (also known as PTP1C, HCP and SHP), which is primarily expressed in hematopoietic cells and characterized by the presence of two SH2 domains N terminal to the PTP domain. A second and much more widely expressed PTP with SH2 domains, SHPTP2 (also designated PTP1D and Syp), has been identified. SHP2 is a protein tyrosine phosphatase that is widely expressed and plays a regulatory role in various cell signaling events that are important for many cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. 
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                                            基因ID
- 3636
- 
                                            途径
- Platelet-derived growth Factor Receptor Signaling
 抗原
- 
                    
 
                                     
                                     
                                    