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CBLN1 抗体 (C-Term)

This anti-CBLN1 antibody is a 兔 多克隆 antibody detecting CBLN1 in WB, IF 和 EIA. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN500535
发货至: 中国

Quick Overview for CBLN1 抗体 (C-Term) (ABIN500535)

抗原

See all CBLN1 抗体
CBLN1 (Cerebellin 1 Precursor (CBLN1))

适用

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人, 大鼠, 小鼠

宿主

  • 18
  • 2

克隆类型

  • 18
  • 2
多克隆

标记

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This CBLN1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 5
    • 2
    • 1
    • 1
    • 1
    C-Term

    特异性

    This antibody detects Precerebellin at C-term.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Peptide affinity chromatography

    免疫原

    Precerebellin antibody was raised against a 16 amino acid peptide from near the carboxy- terminus human precerebellin.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 2 - 4 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CBLN1 (Cerebellin 1 Precursor (CBLN1))

    别名

    Cerebellin-1

    背景

    Precerebellin is the precursor of the brain-specific hexadecapeptide cerebellin, a protein with substantial similarity to the globular region of the B chain of complement component C1q (1). Cerebellin exerts neuromodulatory functions by directly stimulating norepinephrine release via the adenylate cyclase/pka- dependent signaling pathway (2), and indirectly enhances adrenocortical secretion in vivo, through a paracrine mechanism involving medullary catecholamine release (3). The active form of precerebellin is highly enriched in postsynaptic structures of cerebellar Purkinje cells in cartwheel neurons of the dorsal cochlear nucleus (4). Because precerebellin belongs to the C1q/tumor necrosis factor superfamily of secreted proteins and has similarity to adiponectin and CTRP3, it has been suggested that precerebellin posseses functions other than those already stated (5).Synonyms: CBLN1, Precerebellin

    基因ID

    869

    NCBI登录号

    NP_004343

    UniProt

    P23435
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