PPPDE1 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for PPPDE1 抗体 (C-Term) (ABIN500519)
抗原
See all PPPDE1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
特异性
- This antibody detects PNAS4.
-
交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
-
纯化方法
- Peptide affinty chromatography
-
免疫原
- PNAS4 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human PNAS4.
-
亚型
- IgG
-
-
anti-PPPDE Peptidase Domain Containing 1 (PPPDE1) (Internal Region) antibody
Verified PPPDE1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-PPPDE Peptidase Domain Containing 1 (PPPDE1) (C-Term) antibodyPPPDE1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
缓冲液
- PBS containing 0.02 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
-
-
- PPPDE1 (PPPDE Peptidase Domain Containing 1 (PPPDE1))
-
别名
- PPPDE1
-
背景
- PNAS4 is a highly conserved protein that shares high homology from plants to animals. It was initially identified as a putative apoptosis-related protein in the human acute promyelocytic leukemia cell line NB4. PNAS4 is activated during the early response to DNA damage and can inhibit proliferation via apoptosis when overexpressed in some tumor cells such as U2OS, SKOV3, and A549. PNAS4 inhibits tumor cell proliferation through the following mechanisms: (i) overexpression of PNAS4 causes S phase arrest by regulating the expression of cell cycle-related proteins and (ii) PNAS4 induces apoptosis through the mitochondrial apoptosis pathway. Recent evidence has shown that PNAS4 may be involved in the genesis of some cancers and could be a potential candidate for lung cancer therapy alone or in combination with gemcitabine. At least two isoforms of PNAS4 are known to exist.Synonyms: C1orf121, CGI-146, FAM152A, PNAS-4, PNAS4, PPPDE peptidase domain-containing protein 1
-
基因ID
- 51029
-
NCBI登录号
- NP_057160
-
UniProt
- Q9BSY9
抗原
-
