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PIGY 抗体 (C-Term)

This 兔 多克隆 anti-PIGY antibody specifically detects PIGY in WB, IHC (p) 和 EIA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN500497
发货至: 中国
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Quick Overview for PIGY 抗体 (C-Term) (ABIN500497)

抗原

See all PIGY 抗体
PIGY (Phosphatidylinositol Glycan Anchor Biosynthesis, Class Y (PIGY))

适用

人, 小鼠

宿主

  • 6

克隆类型

  • 6
多克隆

标记

  • 6
This PIGY antibody is un-conjugated

应用范围

  • 6
  • 3
  • 3
  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term

    特异性

    This antibody detects PIG-Y at C-term. It only detects isoform 1 of PIG-Y.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse

    纯化方法

    Peptide affinity chromatography

    免疫原

    PIG-Y antibody was raised against a 16 amino acid peptide near the carboxy terminus of human PIG-Y.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    PIGY (Phosphatidylinositol Glycan Anchor Biosynthesis, Class Y (PIGY))

    别名

    PIGY

    背景

    Glycosylphosphatidylinositol (GPI) lipid anchoring is an important post-translational modification of proteins that takes place in the endoplasmic reticulum. The synthesis of GPI is initiated by GPI-N-acetylglucosaminyltransferase (GPI-GnT), a complex of proteins including PIG-A, PIG-H, PIG-C, GPI1, and DPM2. PIG-Y, the mammalian homolog to yeast Eri1p, is also thought to be involved in the biosynthesis of GPI. The PIG-Y gene encodes two proteins, one of which arises from leaky scanning of the mRNA. Despite its predicted molecular weight, PIG-Y often migrates at 28-30 kDa in SDS-PAGE.Synonyms: PIG-Y, Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y, Phosphatidylinositol-glycan biosynthesis class Y protein

    基因ID

    84992

    NCBI登录号

    NP_001036081

    UniProt

    Q3MUY2

    途径

    Inositol Metabolic Process
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