PIGY 抗体 (C-Term)
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Quick Overview for PIGY 抗体 (C-Term) (ABIN500497)
抗原
See all PIGY 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects PIG-Y at C-term. It only detects isoform 1 of PIG-Y.
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交叉反应 (详细)
- Species reactivity (tested):Human, mouse
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纯化方法
- Peptide affinity chromatography
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免疫原
- PIG-Y antibody was raised against a 16 amino acid peptide near the carboxy terminus of human PIG-Y.
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亚型
- IgG
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应用备注
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ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- PIGY (Phosphatidylinositol Glycan Anchor Biosynthesis, Class Y (PIGY))
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别名
- PIGY
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背景
- Glycosylphosphatidylinositol (GPI) lipid anchoring is an important post-translational modification of proteins that takes place in the endoplasmic reticulum. The synthesis of GPI is initiated by GPI-N-acetylglucosaminyltransferase (GPI-GnT), a complex of proteins including PIG-A, PIG-H, PIG-C, GPI1, and DPM2. PIG-Y, the mammalian homolog to yeast Eri1p, is also thought to be involved in the biosynthesis of GPI. The PIG-Y gene encodes two proteins, one of which arises from leaky scanning of the mRNA. Despite its predicted molecular weight, PIG-Y often migrates at 28-30 kDa in SDS-PAGE.Synonyms: PIG-Y, Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y, Phosphatidylinositol-glycan biosynthesis class Y protein
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基因ID
- 84992
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NCBI登录号
- NP_001036081
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UniProt
- Q3MUY2
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途径
- Inositol Metabolic Process
抗原
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