DNAJB2 抗体 (AA 21-120) (AbBy Fluor® 680)
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北京 101111
Quick Overview for DNAJB2 抗体 (AA 21-120) (AbBy Fluor® 680) (ABIN5004897)
抗原
See all DNAJB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-120
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预测反应
- Human,Mouse,Rat,Cow,Sheep,Pig,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human HSJ1/DNAJB2
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- DNAJB2 (DnaJ (Hsp40) Homolog, Subfamily B, Member 2 (DNAJB2))
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别名
- HSJ1
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背景
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Synonyms: Descriptions, DnaJ Hsp40 homolog subfamily B member 2, DnaJ homolog subfamily B member 2, DnaJ protein homolog 1, DNAJB2, Heat shock 40 kDa protein 3, Heat shock protein J1, Heat shock protein neuronal DNAJ like 1, HSJ 1, HSJ1, HSPF3, DNJB2_HUMAN.
Background: The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. The proteins contain cysteine rich regions that are composed of zinc fingers that form a peptide binding domain responsible for the chaperone function. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJB2 (DnaJ homolog subfamily B member 2), also known as HSJ1 or HSPF3, is expressed almost exclusively in the brain, with the highest levels in the frontal cortex and hippocampus. Two isoforms are produced due to alternative splicing.
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基因ID
- 3300
抗原
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