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PERP 抗体 (C-Term)

This anti-PERP antibody is a 兔 多克隆 antibody detecting PERP in WB, IF 和 EIA. Suitable for 人.
产品编号 ABIN500475
发货至: 中国

Quick Overview for PERP 抗体 (C-Term) (ABIN500475)

抗原

See all PERP 抗体
PERP (TP53 Apoptosis Effector (PERP))

适用

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宿主

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克隆类型

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多克隆

标记

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This PERP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
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    C-Term

    特异性

    This antibody detects PERP.

    交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    DEAE purified

    免疫原

    PERP antibody was raised against a synthetic peptide corresponding to amino acids near the carboxy terminus of human PERP, which differ from the mouse sequence by three amino acids (7-9).

    亚型

    IgG
  • 应用备注

    ELISA. Western blot. Immunoflourescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    PERP (TP53 Apoptosis Effector (PERP))

    别名

    PERP

    背景

    The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 network, including Chk2 , p53R2 (2), p53AIP1 (3), Noxa (4), PIDD (5), PID/MTA2 (6), MTBP (7) and PERP (8), were identified and their genes were cloned recently. PERP, also termed PIGPC1 and THW, is a plasma membrane protein (8-10). p53 binds to the promoter of PERP and transcriptionally activates PERP gene then the translated PERP protein mediates the p53 induced apoptosis (8). The expression of PERP causes cell death. PERP is a mediator of p53 induced apoptosis. PERP has sequence similarity to PMP-22/gas3 and is a new member of the PMP-22/gas3 family (8).Synonyms: KCP-1, KCP1, KRTCAP1, Keratinocyte-associated protein 1, P53-induced protein PIGPC1, PERP, PIGPC1, THW, Transmembrane protein THW, p53 apoptosis effector related to PMP-22

    基因ID

    64058

    UniProt

    Q9JK95

    途径

    Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity
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