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PDCD1LG2 抗体 (Center)

PDCD1LG2 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500469
发货至: 中国
  • 抗原 See all PDCD1LG2 抗体
    PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
    抗原表位
    • 9
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    适用
    • 69
    • 24
    • 9
    • 3
    人, 小鼠, 大鼠
    宿主
    • 48
    • 25
    • 11
    • 1
    克隆类型
    • 44
    • 38
    • 1
    多克隆
    标记
    • 50
    • 9
    • 7
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PDCD1LG2 antibody is un-conjugated
    应用范围
    • 50
    • 38
    • 38
    • 30
    • 17
    • 10
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects CD273 / PDL2.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat
    纯化方法
    Peptide affinity chromatography
    免疫原
    PDL-2 antibody was raised against a 16 amino acid peptide from near the center of human PDL-2.
    亚型
    IgG
    Top Product
    Discover our top product PDCD1LG2 Primary Antibody
  • 应用备注
    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
    别名
    CD273 / PDL2 (PDCD1LG2 产品)
    别名
    PDL2 antibody, B7DC antibody, Btdc antibody, CD273 antibody, PD-L2 antibody, PDCD1L2 antibody, bA574F11.2 antibody, B7-DC antibody, F730015O22Rik antibody, programmed cell death 1 ligand 2 antibody, PDCD1LG2 antibody, Pdcd1lg2 antibody
    背景
    Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by co gnate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2, both of which are thought act as a negative regulator of T cell activation. However, it has been suggested that PDL-2 can act to stimulate an immunogenic response through and alternative receptor from PD-1. At least three isoforms of PDL-2 are known to exist, this antibody is specific to the largest isoform.Synonyms: B7DC, PD-1-ligand 2, PD-L2, PDCD1 ligand 2, PDCD1L2, PDCD1LG2, Programmed cell death 1 ligand 2, Programmed death ligand 2
    基因ID
    80380
    NCBI登录号
    NP_079515
    UniProt
    Q9BQ51
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