PDCD5 抗体 (C-Term)
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Quick Overview for PDCD5 抗体 (C-Term) (ABIN500463)
抗原
See all PDCD5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects PDCD5 at C-term.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Peptide affinity chromatography
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免疫原
- PDCD5 antibody was raised against a 21 amino acid peptide from near the carboxy terminus of human PDCD5.
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亚型
- IgG
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anti-Programmed Cell Death 5 (PDCD5) (C-Term) antibody
PDCD5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 5 (PDCD5) (AA 1-125) antibodyPDCD5 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 5 (PDCD5) (AA 1-125) antibodyPDCD5 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 5 (PDCD5) (AA 2-125) antibodyPDCD5 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 5 (PDCD5) antibodyPDCD5 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 5 (PDCD5) (AA 1-125) antibodyPDCD5 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Programmed Cell Death 5 (PDCD5) antibodyPDCD5 适用: 人 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 5 (PDCD5) (N-Term) antibodyPDCD5 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 1 μg/mL. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- PDCD5 (Programmed Cell Death 5 (PDCD5))
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别名
- PDCD5
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背景
- Programmed cell death 5 (PDCD5), a human apoptosis-related protein, is thought to play an early and universal role in apoptosis. PDCD5 is widely expressed and is upregulated in cells undergoing apoptosis, where it translocates rapidly from the cytoplasm to the nucleus. PDCD5 has a compact core structure of low flexibility with two mobile alpha-helices at N-terminal and a flexible unstructured C-terminal region. The charged residues are crucial for the ability of apoptosis-promoting and cell translocation of the protein. PDCD5 can facilitate apoptosis and enhance TAJ/TROY-induced paraptosis-like cell death. PDCD5 may play a dual role in the Tip60 pathway. It interacts with Tip60 and functions as a Tip60 co-activator to promote apoptosis. The nucleotide polymorphisms in the 5?-upstream region of PDCD5 affect promoter activity and the susceptibility of a Chinese population to develop chronic myelogenous leukemia and may represent a novel tumor suppressor gene influencing lung cancer.Synonyms: Programmed cell death protein 5, TF-1 cell apoptosis-related protein 19, TFAR19
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基因ID
- 9141
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NCBI登录号
- NP_004699
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UniProt
- O14737
抗原
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