PCDH18 抗体 (N-Term)
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Quick Overview for PCDH18 抗体 (N-Term) (ABIN500455)
抗原
See all PCDH18 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects PCDH18. It is predicted to not cross-react with PCDH12.
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交叉反应 (详细)
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Peptide affinity chromatography
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免疫原
- PCDH12 antibody was raised against a 17 amino acid peptide near the amino terminus of human PCDH12.
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亚型
- IgG
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应用备注
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ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- PCDH18 (Protocadherin 18 (PCDH18))
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别名
- PCDH18
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背景
- Protocadherins comprise the largest group within the cadherin family of calcium-dependent cell-cell adhesion molecules. Protocadherin 18 (PCDH18) was initially identified through screening of human and mouse ESTs using conserved cytoplasmic domain motifs. Tissue screening revealed PCDH18 broad expression in tissues such as brain, liver, heart, kidney, lung, and trachea. PCDH18 expression is also temporally and spatially regulated in the mouse embryonic brain and interacts with Disabled-1, an intracellular adapter protein involved in neuronal migration and cell positioning during mammalian brain development. PCDH18 was also found to be expressed in the developing zebrafish neural tube and central nervous system, lending support to the hypothesis that PCDH18 may play a role during brain development. At least three isoforms of PCDH18 are known to exist.Synonyms: KIAA1562, Protocadherin 18, Protocadherin-18
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基因ID
- 54510
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NCBI登录号
- NP_061908
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UniProt
- Q9HCL0
抗原
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