PCDH12 抗体 (N-Term)
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Quick Overview for PCDH12 抗体 (N-Term) (ABIN500453)
抗原
See all PCDH12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects PCDH12. It is predicted to not cross-react with PCDH18.
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纯化方法
- Peptide affinity chromatography
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免疫原
- PCDH12 antibody was raised against a 17 amino acid peptide near the amino terminus of human PCDH12.
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亚型
- IgG
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应用备注
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ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- PBS containing 0.02 % sodium azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PCDH12 (Protocadherin 12 (PCDH12))
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别名
- Protocadherin-12 / PCDH12
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背景
- Protocadherins comprise the largest group within the cadherin family of calcium-dependent cell-cell adhesion molecules. Protocadherin 12 (PCDH12) was initially identified through PCR screening of mouse heart microvascular endothelial cell RNA, further experiments revealed its mRNA to be strongly expressed in highly vascularized organs such as lung and kidney, in addition to glycogen-rich trophoblasts in the placenta. PCDH12-null mice are viable and fertile, but show reduced placental and embryonic sizes when compared to wild-type mice. Further studies showed significant expression changes in 2,289 genes, including those involved in tissue morphogenesis, angiogenesis, cell-matrix adhesion and migration, immune response and chromatin remodeling.Synonyms: VE-cad-2, VE-cadherin-2, Vascular cadherin-2, Vascular endothelial cadherin-2
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基因ID
- 51294
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NCBI登录号
- NP_057664
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UniProt
- Q9NPG4
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途径
- Cellular Glucan Metabolic Process
抗原
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