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CUL9 抗体 (C-Term)

This anti-CUL9 antibody is a 兔 多克隆 antibody detecting CUL9 in WB, IF 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN500449
发货至: 中国

Quick Overview for CUL9 抗体 (C-Term) (ABIN500449)

抗原

See all CUL9 抗体
CUL9 (Cullin 9 (CUL9))

适用

  • 24
  • 7
  • 2
  • 2
人, 小鼠

宿主

  • 18
  • 7

克隆类型

  • 18
  • 7
多克隆

标记

  • 25
This CUL9 antibody is un-conjugated

应用范围

  • 24
  • 13
  • 13
  • 8
  • 8
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term

    特异性

    This antibody detects Cullin-9.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse

    纯化方法

    Peptide affinity chromatography

    免疫原

    PARC antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human PARC.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot. Immuncytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CUL9 (Cullin 9 (CUL9))

    别名

    Cullin-9

    背景

    The continued localization of p53 to the nucleus is essential for its function as a tumor suppressor. PARC, a large, Parkin-like ubiquitin ligase has recently been identified as a cytoplasmic anchor protein in p53-associated protein complexes. In the absence of stress, PARC inactivation results in nuclear localization of p53 and activation of p53-dependent apoptosis, while overexpression of this protein promoted cytoplasmic sequestration of p53. Surprisingly, PARC knockout mice were viable and exhibited no obvious phenotype, suggesting that other proteins, such as the highly related cullin family of E3 ubiquitin ligases, may perform similar functions in the absence of PARC. Additionally, it has been suggested that p53 binding to PARC may serve to control PARC function.Synonyms: CUL-9, H7AP1, KIAA0708, PARC, UbcH7-associated protein 1, p53-associated parkin-like cytoplasmic protein

    基因ID

    23113

    NCBI登录号

    NP_055904

    UniProt

    Q8IWT3
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