Hepcidin 25 抗体 (AA 60-84) (AbBy Fluor® 750)
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北京 101111
Quick Overview for Hepcidin 25 抗体 (AA 60-84) (AbBy Fluor® 750) (ABIN5004479)
抗原
See all Hepcidin 25 (HEPC25) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 60-84
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交叉反应
- 人
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Hepcidin 25
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- Hepcidin 25 (HEPC25)
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别名
- Hepcidin 25
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背景
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Synonyms: Hamp, HEPC, HEPC_HUMAN, Hepc20, Hepc25, HEPCIDIN, Hepcidin, Hepcidin 20, Hepcidin 25, Hepcidin antimicrobial peptide, Hepcidin-20, Hepcidin25, HFE2, HFE2B, LEAP 1, LEAP-1, LEAP1, Liver expressed antimicrobial peptide, Liver-expressed antimicrobial peptide 1, PLTR, Putative liver tumor regressor.
Background: The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq, Jul 2008].
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基因ID
- 57817
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UniProt
- P81172
抗原
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