PTPN23 抗体 (AA 1501-1636) (AbBy Fluor® 680)
Quick Overview for PTPN23 抗体 (AA 1501-1636) (AbBy Fluor® 680) (ABIN5004387)
抗原
See all PTPN23 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1501-1636
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交叉反应
- 人, 大鼠
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预测反应
- Mouse,Pig,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human HDPTP
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亚型
- IgG
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anti-Protein Tyrosine Phosphatase, Non Receptor Type 23 (PTPN23) (C-Term) antibody
PTPN23 适用: 人, 大鼠, 小鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Tyrosine Phosphatase, Non Receptor Type 23 (PTPN23) (AA 1230-1450) antibodyPTPN23 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Tyrosine Phosphatase, Non Receptor Type 23 (PTPN23) (AA 1501-1636) antibodyPTPN23 适用: 人, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Tyrosine Phosphatase, Non Receptor Type 23 (PTPN23) (AA 1-577) antibodyPTPN23 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Tyrosine Phosphatase, Non Receptor Type 23 (PTPN23) antibodyPTPN23 适用: 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- PTPN23 (Protein Tyrosine Phosphatase, Non Receptor Type 23 (PTPN23))
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别名
- HDPTP
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背景
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Synonyms: DKFZP564F0923, EC 3.1.3.48, HD PTP, HD-PTP, HDPTP, His domain containing protein tyrosine phosphatase, His domain protein tyrosine phosphatase, His domain-containing protein tyrosine phosphatase, KIAA1471, Protein tyrosine phosphatase non receptor type 23, protein tyrosine phosphatase non-receptor type 23, Protein tyrosine phosphatase TD 14, protein tyrosine phosphatase TD14, PTN23_HUMAN, PTP TD14, PTP-TD14, PTPN 23, PTPN23, Tyrosine protein phosphatase non receptor type 23, Tyrosine-protein phosphatase non-receptor type 23.
Background: HD-PTP is a 1,636 amino acid protein encoded by the human gene PTPN23. HD-PTP belongs to the protein-tyrosine phosphatase family, non-receptor class subfamily. It contains one BRO1 domain, two TPR repeats and one tyrosine-protein phosphatase domain. The C-terminal region contains the PTP-like domain, whereas the N-terminal region contains the two TPR regions. These regions are homologous to the yeast protein, BRO1, which is involved in the mitogen-activated protein kinase signaling pathway. Similarly, HD-PTP is believed to act as a negative regulator of Ras-mediated mitogenic activity and is phosphorylated upon DNA damage, probably by ATM or ATR. HD-PTP protein is differentially modulated by two angiogenic growth factors. While Vascular Endothelial Growth Factor (VEGF) has no affect on protein levels, Fibroblast Growth Factor-2 (FGF-2) induces HD-PTP degradation via the proteasome system.
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基因ID
- 25930
抗原
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