HDAC3 抗体 (AA 31-130) (AbBy Fluor® 750)
Quick Overview for HDAC3 抗体 (AA 31-130) (AbBy Fluor® 750) (ABIN5004348)
抗原
See all HDAC3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 31-130
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Cow,Horse,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human HDAC3/HD3
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亚型
- IgG
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anti-Histone Deacetylase 3 (HDAC3) (AA 299-428) antibody
HDAC3 适用: 人 WB, IHC, IF, IP, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 3 (HDAC3) (C-Term) antibodyHDAC3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 3 (HDAC3) (pSer424) antibodyHDAC3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 3 (HDAC3) (AA 1-428) antibodyHDAC3 适用: 人 WB, ELISA, IHC, IF, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 3 (HDAC3) (AA 319-428) antibodyHDAC3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2A3 unconjugated
anti-Histone Deacetylase 3 (HDAC3) antibodyHDAC3 适用: 人, 小鼠, 大鼠, 犬, 小鸡 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 3 (HDAC3) (C-Term) antibodyHDAC3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 3 (HDAC3) (AA 1-428) antibodyHDAC3 适用: 人 ELISA, IF, IP 宿主: 小鼠 Monoclonal 2F9-4B7 unconjugated
anti-Histone Deacetylase 3 (HDAC3) (AA 31-130) antibodyHDAC3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), IF (cc), FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 3 (HDAC3) antibodyHDAC3 适用: 人 WB, ELISA, IHC 宿主: 兔 Monoclonal 4D4 unconjugated Recombinant Antibody
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应用备注
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- HDAC3 (Histone Deacetylase 3 (HDAC3))
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别名
- HDAC3/HD3
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背景
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Synonyms: HD3, RPD3, RPD3-2, Histone deacetylase 3, SMAP45, HDAC3
Background: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Participates in the BCL6 transcriptional repressor activity by deacetylating the H3 'Lys-27' (H3K27) on enhancer elements, antagonizing EP300 acetyltransferase activity and repressing proximal gene expression. Probably participates in the regulation of transcription through its binding to the zinc-finger transcription factor YY1, increases YY1 repression activity. Required to repress transcription of the POU1F1 transcription factor. Acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation.
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基因ID
- 8841
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UniProt
- O15379
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途径
- Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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