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HDAC3 抗体 (pSer424) (AbBy Fluor® 680)

This anti-HDAC3 antibody is a 兔 多克隆 antibody detecting HDAC3 in WB, IF (p) 和 IF (cc). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5004345
发货至: 中国

Quick Overview for HDAC3 抗体 (pSer424) (AbBy Fluor® 680) (ABIN5004345)

抗原

See all HDAC3 抗体
HDAC3 (Histone Deacetylase 3 (HDAC3))

适用

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人, 小鼠, 大鼠

宿主

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  • 1

克隆类型

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  • 29
多克隆

标记

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This HDAC3 antibody is conjugated to AbBy Fluor® 680

应用范围

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Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
  • 抗原表位

    • 17
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    • 1
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    • 1
    • 1
    • 1
    pSer424

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human HDAC3 around the phosphorylation site of Ser424

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    HDAC3 (Histone Deacetylase 3 (HDAC3))

    别名

    HDAC3

    背景

    Synonyms: HDAC3 phospho S424, HDAC3 phospho Ser424, p-HDAC3 Ser424, RPD3 2, RPD3-2, HD 3, HD3, HDAC 3, Histone deacetylase 3 HD3 RPD3-2, histone deacetylase 3, RPD 3, RPD3, SMAP 45, SMAP-45, SMAP45, HDAC3_HUMAN.

    Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008].

    基因ID

    8841

    途径

    Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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