HCCS 抗体 (AA 51-150) (AbBy Fluor® 750)
Quick Overview for HCCS 抗体 (AA 51-150) (AbBy Fluor® 750) (ABIN5004298)
抗原
See all HCCS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-150
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Dog,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human HCCS
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- HCCS (Holocytochrome C Synthase (HCCS))
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别名
- HCCS
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背景
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Synonyms: CCHL, DKFZp779I1858, EC 4.4.1.17, Holocytochrome c synthase cytochrome c heme lyase, Holocytochrome c type synthase, MCOPS7, OTTHUMP00000022903, OTTHUMP00000022904, OTTHUMP00000022905, OTTMUSP00000021173, OTTMUSP00000021174, RGD1563855, RP23-37L2.1, CCHL_HUMAN.
Background: HCCS is a 79 amino acid protein that may act as a tumor suppressor, promoting the apoptosis of cancer cells. Expressed in leukocytes, lung, spleen, liver, heart, kidney, muscle and uterine cervix, HCCS-1 is down-regulated in cervical cancers. The gene encoding HCCS-1 maps to human chromosome 15q25.1. Encoding more than 700 genes, chromosome 15 is made up of approximately 106 million base pairs and comprises about 3 % of the human genome. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region. Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, which is encoded by chromosome 15. Marfan syndrome is associated with chromosome 15 through the FBN1 gene.
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基因ID
- 3052
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UniProt
- P53701
抗原
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