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NUP107 抗体 (C-Term)

This anti-NUP107 antibody is a 兔 多克隆 antibody detecting NUP107 in WB, IF 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN500395
发货至: 中国

Quick Overview for NUP107 抗体 (C-Term) (ABIN500395)

抗原

See all NUP107 抗体
NUP107 (Nucleoporin 107kDa (NUP107))

适用

  • 40
  • 20
  • 6
  • 1
人, 小鼠, 大鼠

宿主

  • 49
  • 2

克隆类型

  • 48
  • 3
多克隆

标记

  • 28
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This NUP107 antibody is un-conjugated

应用范围

  • 47
  • 23
  • 15
  • 14
  • 7
  • 6
  • 5
  • 4
  • 2
  • 2
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 16
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    特异性

    This antibody detects NUP107 at C-term.

    纯化方法

    Immunoaffinity chromatography

    免疫原

    NUP107 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human NUP107.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 1 - 2 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    PBS containing 0.02 % sodium azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    NUP107 (Nucleoporin 107kDa (NUP107))

    别名

    NUP107

    背景

    The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. The mammalian nucleoporin (NUP)-107 is part of the hetero-oligomeric complex that also contains NUP160, NUP133, NUP96, and mammalian homolog of yeast sec13p. While the majority of the NUP107-160 nuclear pore sub-complex localizes to the nuclear pore, a small fraction is observed at kinetochores and pro-metaphase spindle poles in mitotic cells in association with proteins such as Mad1, Mad2, Bub3 and Cdc20. Immunodepletion of the NUP107-160 complex resulted in defective spindle assembly indicating that it has multiple functions. NUP107 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP107 may be an important drug target in HIV treatment. Multiple isoforms of NUP107 are known to exist.Synonyms: NUP84, Nuclear pore complex protein Nup107, Nucleoporin Nup107

    基因ID

    57122

    UniProt

    P57740

    途径

    Protein targeting to Nucleus
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