NOD2 抗体 (N-Term)
Quick Overview for NOD2 抗体 (N-Term) (ABIN500363)
抗原
See all NOD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects CARD15 / NOD2 at N-term.
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交叉反应 （详细）
- Species reactivity (tested):ELISA.Western blot: 2 to 4 μg/mL.Immunohistochemistry on paraffin sections.
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纯化方法
- Peptide affinity chromatography
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免疫原
- Rabbit NOD2 polyclonal antibody was raised against a synthetic peptide corresponding to 16 amino acids at the amino terminus of human NOD2.
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亚型
- IgG
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anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) (AA 611-910) antibody
NOD2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) (N-Term) antibodyNOD2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) (AA 251-350) antibodyNOD2 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) (AA 460-733) antibodyNOD2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) antibodyNOD2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) (AA 1-1040) antibodyNOD2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) (C-Term) antibodyNOD2 适用: 人 WB, ELISA, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) (AA 251-350) antibody (AbBy Fluor® 488)NOD2 适用: 人 WB, FACS 宿主: 兔 Polyclonal AbBy Fluor® 488
anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) (AA 1-1040) antibodyNOD2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) antibodyNOD2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 2 to 4 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- NOD2 (Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2))
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别名
- CARD15 / NOD2
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背景
- Apaf-1 and NOD1 are members of a new family (1), which are involved in the regulation of apoptosis and immune response. Each of them contains a caspase recruitment domain (CARD) and a nucleotide-binding oligomerization domain (NOD). A third member in this family was recently identified and designated NOD2 (2). NOD2 interacts with RICK via a homophilic CARD-CARD interaction. NOD2 activates NF-κB, which is regulated by its carboxy-terminal leucine-rich repeat domain that acts as an intracellular receptor for components of bacteria. The variants of NOD2, either a frameshift or a missense, were associated with Crohn's disease (3,4) that is a main type of chronic inflammatory bowel disease.Synonyms: Caspase recruitment domain-containing protein 15, IBD1, Inflammatory bowel disease protein 1, Nucleotide-binding oligomerization domain-containing protein 2
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基因ID
- 64127
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UniProt
- Q9HC29
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途径
- Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome
抗原
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