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GLRB 抗体 (AA 51-150)

This anti-GLRB antibody is a 兔 多克隆 antibody detecting GLRB in WB, ELISA, IF (cc), IF (p), ICC, IHC (fro) 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5003557
发货至: 中国

Quick Overview for GLRB 抗体 (AA 51-150) (ABIN5003557)

抗原

See all GLRB 抗体
GLRB (Glycine Receptor, beta (GLRB))

适用

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人, 小鼠, 大鼠

宿主

  • 40
  • 1

克隆类型

  • 40
  • 1
多克隆

标记

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This GLRB antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    • 1
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    AA 51-150

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Dog,Cow,Sheep,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human GLRB

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    GLRB (Glycine Receptor, beta (GLRB))

    别名

    GLRB

    背景

    Synonyms: Glycine receptor subunit beta, GLRB, Glycine receptor 58 kDa subunit

    Background: Glycine receptors are ligand-gated chloride channels. GLRB does not form ligand-gated ion channels by itself, but is part of heteromeric ligand-gated chloride channels. Channel opening is triggered by extracellular glycine (PubMed:8717357, PubMed:15302677, PubMed:16144831, PubMed:22715885, PubMed:25445488, PubMed:11929858, PubMed:23238346). Heteropentameric channels composed of GLRB and GLRA1 are activated by lower glycine levels than homopentameric GLRA1 (PubMed:8717357). Plays an important role in the down-regulation of neuronal excitability (PubMed:11929858, PubMed:23238346). Contributes to the generation of inhibitory postsynaptic currents (PubMed:25445488).

    基因ID

    2743

    UniProt

    P48167
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