GBAS 抗体 (N-Term)
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Quick Overview for GBAS 抗体 (N-Term) (ABIN500353)
抗原
See all GBAS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects NIPSNAP2 / GBAS at N-term. It is predicted to not cross-react with any other members of the NIPSNAP protein family.
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交叉反应 (详细)
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Peptide affinity chromatography
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免疫原
- NIPSNAP2 antibody was raised against a 14 amino acid peptide near the amino terminus of human NIPSNAP2.
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亚型
- IgG
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应用备注
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ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- GBAS (Glioblastoma Amplified Sequence (GBAS))
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别名
- NIPSNAP2 / GBAS
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背景
- The NIPSNAP proteins comprise a family of evolutionarily well-conserved proteins with strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. NIPSNAP2, a novel gene encoding a protein with tyrosine phosphorylation sites and a transmembrane domain, is co-amplified with EGFR in approximately 40 % of glioblastomas, the most common and malignant form of central nervous system tumors. It is widely expressed and most abundant in heart and skeletal muscle. NIPSNAP proteins have been suggested to be important in vesicular transport.Synonyms: Protein NipSnap homolog 2, glioblastoma amplified sequence
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基因ID
- 2631
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UniProt
- O75323
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途径
- Ribonucleoside Biosynthetic Process
抗原
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