GAS2 抗体 (AA 141-240) (AbBy Fluor® 680)
Quick Overview for GAS2 抗体 (AA 141-240) (AbBy Fluor® 680) (ABIN5003213)
抗原
See all GAS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 141-240
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预测反应
- Human,Mouse,Rat,Cow,Sheep,Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human GAS2
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亚型
- IgG
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anti-Growth Arrest-Specific 2 (GAS2) (AA 1-110) antibody
GAS2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4E11 unconjugated
anti-Growth Arrest-Specific 2 (GAS2) (AA 1-100) antibodyGAS2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest-Specific 2 (GAS2) (AA 1-141) antibodyGAS2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest-Specific 2 (GAS2) antibodyGAS2 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest-Specific 2 (GAS2) (AA 1-110) antibodyGAS2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Growth Arrest-Specific 2 (GAS2) (C-Term) antibodyGAS2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest-Specific 2 (GAS2) (AA 64-267) antibodyGAS2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest-Specific 2 (GAS2) antibodyGAS2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest-Specific 2 (GAS2) (AA 1-313) antibodyGAS2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Growth Arrest-Specific 2 (GAS2) (AA 1-313) antibodyGAS2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- GAS2 (Growth Arrest-Specific 2 (GAS2))
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别名
- GAS2
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背景
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Synonyms: GAS 2, GAS-2, Gas2, GAS2_HUMAN, Growth arrest specic 2, Growth arrest specic protein 2, Growth arrest-specic protein 2, MGC32610.
Background: Gas2 is a 313 amino acid protein encoded by the human gene GAS2. Gas2 is thought to play a role in apoptosis by acting as a cell death substrate for caspases. Gas2, a component of the microfilament system, is cleaved by a caspase (caspase-3 and caspase-7) at Asparagine 278 during apoptosis. The cleaved form resulting from this dramatically induces the rearrangement of the Actin cytoskeleton and causes potent changes in the shape of the affected cells. Gas2 is believed to also be involved in the membrane ruffling process. During the G0-G1 transition phase Gas2 can be found phosphorylated on its serine residues. Gas2 is a cytoskeleton and peripheral membrane protein that co-localizes with Actin fibers at the cell border and along the stress fibers in growth-arrested fibroblasts. Gas2 is mainly membrane-associated but when hyperphosphorylated it will accumulate at membrane ruffles. Gas2 is specifically expressed at growth arrest and is ubiquitously expressed with highest levels found in liver, lung and kidney. There is no evidence, however, of Gas2 expression in spleen.
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基因ID
- 2620
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途径
- Caspase Cascade in Apoptosis
抗原
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