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Nanos Homolog 1 抗体 (N-Term)

NANOS1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500316
发货至: 中国
  • 抗原 See all Nanos Homolog 1 (NANOS1) 抗体
    Nanos Homolog 1 (NANOS1)
    抗原表位
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 43
    • 12
    • 6
    • 3
    • 3
    • 1
    宿主
    • 41
    • 1
    • 1
    克隆类型
    • 42
    • 1
    多克隆
    标记
    • 22
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Nanos Homolog 1 antibody is un-conjugated
    应用范围
    • 30
    • 22
    • 17
    • 7
    • 6
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects NANOS1 at N-term.
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Peptide affinity chromatography
    免疫原
    Nanos1 antibody was raised against a 17 amino acid peptide from near the amino terminus of human Nanos1.
    亚型
    IgG
    Top Product
    Discover our top product NANOS1 Primary Antibody
  • 应用备注
    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Nanos Homolog 1 (NANOS1)
    别名
    NANOS1 (NANOS1 产品)
    别名
    NOS1 antibody, nanos1 antibody, fb76c12 antibody, wu:fb93h11 antibody, wu:fb98e07 antibody, wu:fq21a10 antibody, Xcat-2 antibody, nos1 antibody, xnos1 antibody, xcat-2 antibody, LOC100144352 antibody, NANOS1A antibody, nanos C2HC-type zinc finger 1 antibody, nanos homolog 1 antibody, nanos homolog 1 (Drosophila) antibody, nanos homolog 1 L homeolog antibody, Nanos homolog 1 antibody, nanos1 antibody, NANOS1 antibody, nanos1 antibody, Nanos1 antibody, nanos1.L antibody, nano1 antibody, nanos1a antibody
    背景
    Nanos1 is one of three known mammalian homologs to the Drosophila gene nanos. Nanos1 is an RNA-binding protein containing a zinc-finger motif and is expressed in the developing nervous system and continues in the adult brain. Interestingly, unlike mice deficient in either nanos2 or nanos3, mice lacking the nanos1 gene develop normally with no sign of abnormalities. Recently it has been found that expression of nanos1 mRNA is down-regulated by E-cadherin in a human breast cancer cell line and the amino-terminal domain on Nanos1 interacts with the E-cadherin-binding protein p120ctn. Furthermore, overexpression of Nanos1 in human colorectal DLD1 cancer cells functionally abolished cell-cell adhesion, allowing the cancer cells to develop strong migratory and invasive properties. These results suggest that targeting Nanos1 might prove an effective strategy in the treatment of E-cadherin-negative tumors.Synonyms: NOS1, Nanos homolog 1
    基因ID
    340719
    UniProt
    Q8WY41
    途径
    Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction
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