NLRP2 抗体 (C-Term)
Quick Overview for NLRP2 抗体 (C-Term) (ABIN500312)
抗原
See all NLRP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects NALP2.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Peptide affinity chromatography
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免疫原
- NALP2 antibody was raised against a peptide corresponding to 12 amino acids near the carboxy-terminus of human NALP2.
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亚型
- IgG
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anti-NLR Family, Pyrin Domain Containing 2 (NLRP2) (AA 1-1062) antibody
NLRP2 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 2 (NLRP2) (AA 1-220) antibodyNLRP2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 2 (NLRP2) (C-Term) antibodyNLRP2 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 2 (NLRP2) (AA 1-220) antibodyNLRP2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 2 (NLRP2) (C-Term) antibodyVerified NLRP2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 2 (NLRP2) (AA 1-846) antibodyNLRP2 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1B10 unconjugated
anti-NLR Family, Pyrin Domain Containing 2 (NLRP2) (AA 1-1062) antibodyNLRP2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 2 (NLRP2) (AA 150-200) antibodyNLRP2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 2 (NLRP2) antibodyNLRP2 适用: 人, 小鼠, Hamster, 猴 WB, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))
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别名
- NALP2
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背景
- NALP2 belongs to a family of cytoplasmic proteins that have been implicated in cell responses to apoptotic and inflammatory stimuli (1). Unlike the prototypical NALP protein NALP1, NALP2 only contains a NACHT domain, leucine rich repeat (LRR), and pyrin-containing domain (PYD) (2). This protein interacts with the adapter protein ASC in addition to CARD8 and caspase-1 to form an inflammasome with high proIL-1Β-processing activity and is thought to function as a modulator of NF-ΚB and procaspase-1 activation in macrophages (2,3). It has also been suggested that NALP2, in addition to other NALP family members, can act as innate sensors of pathogens in a manner similar to the toll-like receptors (TLRs) (4). At least two alternatively spliced transcript variants encoding distinct isoforms have been found for NALP2.Synonyms: LRR and PYD domains-containing protein 2, NACHT, NBS1, NLRP2, PAN1, PYPAF2
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基因ID
- 55655
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NCBI登录号
- NP_060322
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UniProt
- Q9NX02
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途径
- Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
抗原
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