C21ORF45 抗体 (AbBy Fluor® 680)
Quick Overview for C21ORF45 抗体 (AbBy Fluor® 680) (ABIN5002479)
抗原
See all C21ORF45 (MIS18A) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human FASP1/C21orf45
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亚型
- IgG
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anti-MIS18 Kinetochore Protein Homolog A (MIS18A) (N-Term) antibody
MIS18A 适用: 人, 大鼠, Cow, 犬, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-MIS18 Kinetochore Protein Homolog A (MIS18A) (N-Term) antibodyMIS18A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- IF(IHC-P) 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- C21ORF45 (MIS18A) (MIS18 Kinetochore Protein Homolog A (MIS18A))
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别名
- FASP1
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背景
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Synonyms: B28, C21orf46, FASP1, hMis18alpha, MaFF interacting protein, MAFIP, MIS18A, Protein Mis18 alpha, MS18A_HUMAN.
Background: Mapping to chromosome 21, the FASP1 gene (FAPP1-associated protein 1) encodes a 233 amino acid protein that is homologous to the fission yeast protein Mis18. In yeast, Mis18 is localized to the centrosome and forms a complex with Mis16 to maintain the deacetylated state of histones specifically in the central core of centromeres. FASP1, also known as Protein Mis18-alpha and C21orf45, is required for the recruitment of CENP-A to centrosomes and is thereby essential for normal chromosome segregation during mitosis. With expression in testis, FASP1 exists as a homodimer, a heterodimer with MIS18B or is present in a complex containing other Mis18 family members. FASP1 has been shown to bind to pp5644 in Hela cells, where overexpression of pp5644 leads to inhibited growth and colony formation.
抗原
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