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MOAP1 抗体 (Center)

MOAP1 适用: 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500228
发货至: 中国
  • 抗原 See all MOAP1 抗体
    MOAP1 (Modulator of Apoptosis 1 (MOAP1))
    抗原表位
    • 7
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    Center
    适用
    • 25
    • 4
    • 2
    人, 小鼠
    宿主
    • 22
    • 5
    克隆类型
    • 24
    • 3
    多克隆
    标记
    • 17
    • 2
    • 2
    • 2
    • 2
    • 2
    This MOAP1 antibody is un-conjugated
    应用范围
    • 25
    • 16
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects Modulator of apoptosis 1 at enter.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse
    纯化方法
    Peptide affinity chromatography
    免疫原
    MAP-1 antibody was raised against a 15 amino acid peptide from near the center of human MAP-1.
    亚型
    IgG
    Top Product
    Discover our top product MOAP1 Primary Antibody
  • 应用备注
    ELISA. Western blot: 1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    MOAP1 (Modulator of Apoptosis 1 (MOAP1))
    别名
    MOAP1 (MOAP1 产品)
    背景
    Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer (reviewed in 1). Members of the Bcl-2 family are known to be critical regulators of this process. These proteins are characterized by the presence of several conserved motifs termed Bcl-2 homology (BH) domains (reviewed in 2 and 3). A related protein termed MAP-1 has recently been identified. This protein contains a BH3-like domain and induces caspase-dependent apoptosis in mammalian cells when overexpressed. It forms homodimers and associates with Bcl-2 family members such as Bax, Bcl-2, and Bcl-XL in vitro and in vivo (4). It has been suggested that MAP-1 associates with the tumor suppressor RASSF1A following death receptor activation, allowing a conformational change in Bax that leads to cellular apoptosis (5).Synonyms: MAP-1, MAP1, Modulator of apoptosis 1
    基因ID
    64112
    NCBI登录号
    NP_071434
    UniProt
    Q96BY2
    途径
    Positive Regulation of Endopeptidase Activity
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