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LRRC19 抗体 (C-Term)

This anti-LRRC19 antibody is a 兔 多克隆 antibody detecting LRRC19 in WB, IF 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN500196
发货至: 中国

Quick Overview for LRRC19 抗体 (C-Term) (ABIN500196)

抗原

See all LRRC19 抗体
LRRC19 (Leucine Rich Repeat Containing 19 (LRRC19))

适用

  • 43
  • 12
  • 1
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  • 1
人, 小鼠

宿主

  • 43

克隆类型

  • 43
多克隆

标记

  • 12
  • 4
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  • 1
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  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
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This LRRC19 antibody is un-conjugated

应用范围

  • 17
  • 15
  • 13
  • 13
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 15
    • 8
    • 5
    • 4
    • 1
    • 1
    • 1
    C-Term

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse

    纯化方法

    Peptide affinity chromatography

    免疫原

    LRRC19 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human LRRC19.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody (in aliquots) at -20 °C.
  • 抗原

    LRRC19 (Leucine Rich Repeat Containing 19 (LRRC19))

    别名

    LRRC19

    背景

    LRRC19 is a member of the extracellular leucine-rich repeat superfamily, a family of proteins that are thought to have diverse functions such as cell adhesion, signaling, and innate immunity. LRRC19 is closely related to the Toll-like receptors (TLRs), especially TLR3. LRRC19 does not contain a cytoplasmic Toll/IL-1 receptor (TIR) domain, but can activate NF-kB and induce the production of proinflammatory cytokines after stimulation with the TLR3 and other TLR ligands, suggesting that LRRC19 may play a role in the recognition and the response to certain pathogenic microorganisms. LRRC19 has also been suggested to be a potential biomarker for pancreatic tumor sensitivity to the anti-cancer, small molecule Src inhibitor AZD0530.Synonyms: Leucine-rich repeat-containing protein 19

    基因ID

    64922

    NCBI登录号

    NP_075052

    UniProt

    Q9H756
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