LRRC19 抗体 (C-Term)
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Quick Overview for LRRC19 抗体 (C-Term) (ABIN500196)
抗原
See all LRRC19 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应 (详细)
- Species reactivity (tested):Human, mouse
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纯化方法
- Peptide affinity chromatography
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免疫原
- LRRC19 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human LRRC19.
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亚型
- IgG
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应用备注
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ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- LRRC19 (Leucine Rich Repeat Containing 19 (LRRC19))
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别名
- LRRC19
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背景
- LRRC19 is a member of the extracellular leucine-rich repeat superfamily, a family of proteins that are thought to have diverse functions such as cell adhesion, signaling, and innate immunity. LRRC19 is closely related to the Toll-like receptors (TLRs), especially TLR3. LRRC19 does not contain a cytoplasmic Toll/IL-1 receptor (TIR) domain, but can activate NF-kB and induce the production of proinflammatory cytokines after stimulation with the TLR3 and other TLR ligands, suggesting that LRRC19 may play a role in the recognition and the response to certain pathogenic microorganisms. LRRC19 has also been suggested to be a potential biomarker for pancreatic tumor sensitivity to the anti-cancer, small molecule Src inhibitor AZD0530.Synonyms: Leucine-rich repeat-containing protein 19
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基因ID
- 64922
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NCBI登录号
- NP_075052
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UniProt
- Q9H756
抗原
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