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LIPE 抗体 (C-Term)

LIPE 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500178
发货至: 中国
  • 抗原 See all LIPE 抗体
    LIPE (Lipase, Hormone-Sensitive (LIPE))
    抗原表位
    • 15
    • 13
    • 12
    • 9
    • 9
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 70
    • 56
    • 56
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 85
    • 5
    • 1
    • 1
    克隆类型
    • 82
    • 10
    多克隆
    标记
    • 44
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    This LIPE antibody is un-conjugated
    应用范围
    • 56
    • 27
    • 19
    • 15
    • 14
    • 14
    • 5
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects LIPE.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat
    纯化方法
    Peptide affinity chromatography
    免疫原
    Lipe antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human lipe.
    亚型
    IgG
    Top Product
    Discover our top product LIPE Primary Antibody
  • 应用备注
    ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    LIPE (Lipase, Hormone-Sensitive (LIPE))
    别名
    LIPE (LIPE 产品)
    别名
    ADAP antibody, PRO0823 antibody, SLAP-130 antibody, HSL antibody, LHS antibody, hsl antibody, LIPE antibody, 4933403G17Rik antibody, A antibody, CG11055 antibody, Dmel\CG11055 antibody, anon-56Ea antibody, dHSL antibody, lipe antibody, si:dkey-3n22.7 antibody, FYN binding protein 1 antibody, lipase E, hormone sensitive type antibody, lipase, hormone-sensitive antibody, lipase, hormone-sensitive L homeolog antibody, lipase, hormone sensitive antibody, Hormone-sensitive lipase antibody, lipase, hormone-sensitive a antibody, FYB1 antibody, LIPE antibody, Lipe antibody, lipe antibody, lipe.L antibody, Hsl antibody, lipea antibody
    背景
    Although initially described as an adipocyte-specific triacylglycerol lipase, lipe (also known as hormone-specific lipase or HSL) is expressed in multiple tissues and cell lines. It plays multiple roles in lipid metabolism, including hormone-stimulated lipolysis in adipose tissue and the hydrolysis of cholesterol esters. Lipe is expressed as a long and a short form, generated by use of alternative translational start codons. The long form is expressed in steroidogenic tissues such as testis, where it converts cholesterol esters to free cholesterol for steroid hormone production. The short form is expressed in adipose tissue, among others, where it hydrolyzes stored triglycerides to free fatty acids. Recently, it was observed that the lack of lipe in genetically obese leptin-null mice inhibited obesity and adipogenesis, suggesting that lipe plays a major role in adipocyte proliferation.Synonyms: EC=3.1.1.79, HSL, Hormone-sensitive lipase, LIPE
    基因ID
    3991
    UniProt
    Q05469
    途径
    AMPK Signaling, Monocarboxylic Acid Catabolic Process, Lipid Metabolism
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