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LIPE 抗体 (C-Term)

This anti-LIPE antibody is a 兔 多克隆 antibody detecting LIPE in WB, IHC (p) 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN500178
发货至: 中国

Quick Overview for LIPE 抗体 (C-Term) (ABIN500178)

抗原

See all LIPE 抗体
LIPE (Lipase, Hormone-Sensitive (LIPE))

适用

  • 70
  • 51
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  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 84
  • 5
  • 5
  • 1

克隆类型

  • 81
  • 14
多克隆

标记

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  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This LIPE antibody is un-conjugated

应用范围

  • 66
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  • 15
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  • 5
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  • 1
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 15
    • 13
    • 9
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    • 5
    • 5
    • 4
    • 4
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    • 2
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    • 2
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    • 1
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    • 1
    • 1
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    特异性

    This antibody detects LIPE.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Peptide affinity chromatography

    免疫原

    Lipe antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human lipe.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    LIPE (Lipase, Hormone-Sensitive (LIPE))

    别名

    LIPE

    背景

    Although initially described as an adipocyte-specific triacylglycerol lipase, lipe (also known as hormone-specific lipase or HSL) is expressed in multiple tissues and cell lines. It plays multiple roles in lipid metabolism, including hormone-stimulated lipolysis in adipose tissue and the hydrolysis of cholesterol esters. Lipe is expressed as a long and a short form, generated by use of alternative translational start codons. The long form is expressed in steroidogenic tissues such as testis, where it converts cholesterol esters to free cholesterol for steroid hormone production. The short form is expressed in adipose tissue, among others, where it hydrolyzes stored triglycerides to free fatty acids. Recently, it was observed that the lack of lipe in genetically obese leptin-null mice inhibited obesity and adipogenesis, suggesting that lipe plays a major role in adipocyte proliferation.Synonyms: EC=3.1.1.79, HSL, Hormone-sensitive lipase, LIPE

    基因ID

    3991

    UniProt

    Q05469

    途径

    AMPK Signaling, Monocarboxylic Acid Catabolic Process, Lipid Metabolism
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