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LGI4 抗体 (C-Term)

LGI4 适用: 人, 小鼠, 大鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500160
发货至: 中国
  • 抗原 See all LGI4 抗体
    LGI4 (Leucine-Rich Repeat LGI Family, Member 4 (LGI4))
    抗原表位
    • 15
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 27
    • 9
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 27
    • 2
    克隆类型
    • 27
    • 2
    多克隆
    标记
    • 11
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LGI4 antibody is un-conjugated
    应用范围
    • 24
    • 13
    • 13
    • 10
    • 4
    • 4
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects LGI4 at C-term (only the larger form). It is predicted to be specific to LGI4 and not recognize other LGI proteins.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat
    纯化方法
    Peptide affinity chromatography
    免疫原
    LGI4 antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human LGI4.
    亚型
    IgG
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    Discover our top product LGI4 Primary Antibody
  • 应用备注
    ELISA. Western blot: 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    LGI4 (Leucine-Rich Repeat LGI Family, Member 4 (LGI4))
    别名
    LGI4 (LGI4 产品)
    别名
    Lgil3 antibody, clp antibody, LGIL3 antibody, leucine rich repeat LGI family member 4 antibody, leucine-rich repeat LGI family, member 4 antibody, LGI4 antibody, Lgi4 antibody
    背景
    The leucine-rich, glioma inactivated gene 4 (LGI4) is a member of the LGI family in which LGI1 is the exemplar. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI4 have not been found to be associated with ADTLE. However, the LGI4 gene is located in a region linked to benign familial infantile convulsions. Further study revealed that a GC-to-AT polymorphism was correlated with childhood absence epilepsy. Other studies showed that decreasing LGI4 expression in cultured cells inhibits myelination, indicating that LGI4 may play a role in neural development. Two isoforms of LGI4 are known to exist.Synonyms: LGI1-like protein 3, LGI4, LGIL3, Leucine-rich glioma-inactivated protein 4, Leucine-rich repeat LGI family member 4
    基因ID
    163175
    UniProt
    Q8N135
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