LGI4 抗体 (C-Term)
This anti-LGI4 antibody is a 兔 多克隆 antibody detecting LGI4 in WB 和 EIA. Suitable for 人, 小鼠 和 大鼠.
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Quick Overview for LGI4 抗体 (C-Term) (ABIN500160)
抗原
See all LGI4 抗体
LGI4
(Leucine-Rich Repeat LGI Family, Member 4 (LGI4))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This LGI4 antibody is un-conjugated
应用范围
Western Blotting (WB), Enzyme Immunoassay (EIA)
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抗原表位
- C-Term
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特异性
- This antibody detects LGI4 at C-term (only the larger form). It is predicted to be specific to LGI4 and not recognize other LGI proteins.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Peptide affinity chromatography
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免疫原
- LGI4 antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human LGI4.
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亚型
- IgG
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anti-Leucine-Rich Repeat LGI Family, Member 4 (LGI4) (AA 292-412) antibody
LGI4 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat LGI Family, Member 4 (LGI4) (Internal Region) antibodyLGI4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- LGI4 (Leucine-Rich Repeat LGI Family, Member 4 (LGI4))
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别名
- LGI4
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背景
- The leucine-rich, glioma inactivated gene 4 (LGI4) is a member of the LGI family in which LGI1 is the exemplar. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI4 have not been found to be associated with ADTLE. However, the LGI4 gene is located in a region linked to benign familial infantile convulsions. Further study revealed that a GC-to-AT polymorphism was correlated with childhood absence epilepsy. Other studies showed that decreasing LGI4 expression in cultured cells inhibits myelination, indicating that LGI4 may play a role in neural development. Two isoforms of LGI4 are known to exist.Synonyms: LGI1-like protein 3, LGI4, LGIL3, Leucine-rich glioma-inactivated protein 4, Leucine-rich repeat LGI family member 4
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基因ID
- 163175
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UniProt
- Q8N135
抗原
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