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LGI3 抗体 (Center)

LGI3 适用: 人, 小鼠, 大鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500158
发货至: 中国
  • 抗原 See all LGI3 抗体
    LGI3 (Leucine-Rich Repeat LGI Family, Member 3 (LGI3))
    抗原表位
    • 15
    • 7
    • 1
    • 1
    • 1
    • 1
    Center
    适用
    • 19
    • 18
    • 13
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 27
    • 2
    克隆类型
    • 28
    • 1
    多克隆
    标记
    • 10
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LGI3 antibody is un-conjugated
    应用范围
    • 29
    • 13
    • 13
    • 12
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects LGI3 at center. It will recognize both isoforms. The antibody is predicted to be specific to LGI3 and not recognize other LGI proteins. The observed higher molecular weight band may represent a post-translationally modified form of LGI3.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat
    纯化方法
    Peptide affinity chromatography
    免疫原
    LGI3 antibody was raised against a 12 amino acid peptide from near the center of human LGI3.
    亚型
    IgG
    Top Product
    Discover our top product LGI3 Primary Antibody
  • 应用备注
    ELISA. Western blot: 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    LGI3 (Leucine-Rich Repeat LGI Family, Member 3 (LGI3))
    别名
    LGI3 (LGI3 产品)
    别名
    si:ch211-198o12.2 antibody, LGIL4 antibody, AI841179 antibody, AW049851 antibody, leucine rich repeat LGI family member 3 antibody, leucine-rich repeat LGI family, member 3 antibody, LGI3 antibody, lgi3 antibody, Lgi3 antibody
    背景
    The leucine-rich, glioma inactivated gene 3 (LGI3) is a member of the LGI family in which LGI1 is the exemplar. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI3 have not been found to be associated with ADTLE. LGI3 expression is induced in rat astrocyte cultures by the amyloid beta (Ab) peptide and accumulated on neuronal plasma membranes of aged monkey brains and co-localized with Ab. Two isoforms of LGI3 are known to exist.Synonyms: LGI1-like protein 4, LGI3, LGIL4, Leucine-rich glioma-inactivated protein 3, Leucine-rich repeat LGI family member 3
    基因ID
    203190
    UniProt
    Q8N145
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