LGI3 抗体 (Center)
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北京 101111
Quick Overview for LGI3 抗体 (Center) (ABIN500158)
抗原
See all LGI3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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特异性
- This antibody detects LGI3 at center. It will recognize both isoforms. The antibody is predicted to be specific to LGI3 and not recognize other LGI proteins. The observed higher molecular weight band may represent a post-translationally modified form of LGI3.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Peptide affinity chromatography
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免疫原
- LGI3 antibody was raised against a 12 amino acid peptide from near the center of human LGI3.
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亚型
- IgG
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anti-Leucine-Rich Repeat LGI Family, Member 3 (LGI3) (AA 449-548) antibody
LGI3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Leucine-Rich Repeat LGI Family, Member 3 (LGI3) (AA 261-548) antibodyLGI3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat LGI Family, Member 3 (LGI3) (AA 310-338) antibodyLGI3 适用: 人 WB 宿主: 兔 Polyclonal RB40597 unconjugated
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应用备注
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ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- LGI3 (Leucine-Rich Repeat LGI Family, Member 3 (LGI3))
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别名
- LGI3
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背景
- The leucine-rich, glioma inactivated gene 3 (LGI3) is a member of the LGI family in which LGI1 is the exemplar. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI3 have not been found to be associated with ADTLE. LGI3 expression is induced in rat astrocyte cultures by the amyloid beta (Ab) peptide and accumulated on neuronal plasma membranes of aged monkey brains and co-localized with Ab. Two isoforms of LGI3 are known to exist.Synonyms: LGI1-like protein 4, LGI3, LGIL4, Leucine-rich glioma-inactivated protein 3, Leucine-rich repeat LGI family member 3
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基因ID
- 203190
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UniProt
- Q8N145
抗原
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